Aminobenzoic acids and derivatives
Aobchem 2 5-Dibromo-1-iodo-3-methoxybenzene | 97% | CAS 2385493-51-4 | C7H5Br2IO | 5g
2 5-Dibromo-1-iodo-3-methoxybenzene | 97% | CAS 2385493-51-4 | C7H5Br2IO | 5g
Medchemexpress LLC A-484954 | 142557-61-7 | 99.6% | 289.29 | 10 MG
A-484954 is a highly selective eukaryotic elongation factor-2 kinase (eEF2K) inhibitor with an IC50 of 280 nM. It is intended for research use only.
- Highly selective eEF2K inhibitor
- Inhibits MDA-MB-231 cell viability at IC50 99480 nM
- Causes relaxation in E (+) and E (-) aorta or mesenteric artery
- Inhibits MCT-induced increases in PA pressure, PA hypertrophy, and fibrosis
Medchemexpress LLC Lenvatinib (mesylate) | 857890-39-2 | 99.7% | 522.96 | 25 MG
Lenvatinib mesylate is an oral, multi-targeted tyrosine kinase inhibitor. It inhibits vascular endothelial growth factor receptors (VEGFR1-3), fibroblast growth factor receptors (FGFR1-4), platelet-derived growth factor receptor (PDGFR), KIT, and RET. The compound demonstrates potent antitumor activities.
- Inhibits VEGFR2 with an IC50 of 4 nM
- Inhibits VEGFR3 with an IC50 of 5.2 nM
- Inhibits VEGFR1 with an IC50 of 22 nM
- Inhibits PDGFRα with an IC50 of 51 nM
- Inhibits PDGFRβ with an IC50 of 39 nM
- Inhibits FGFR1 with an IC50 of 46 nM
- Inhibits KIT with an IC50 of 100 nM
- Significantly inhibits local tumor growth and metastasis in preclinical models
Medchemexpress LLC Exatecan mesylate | 169869-90-3 | 101.1% | 531.55 | 50 MG
Exatecan mesylate (DX8951f) is a DNA topoisomerase I inhibitor with an IC50 of 2.2 μM (0.975 μg/mL). It is utilized in cancer research.
- Potent topoisomerase I inhibitor.
- Inhibits proliferation of several cancer cell lines (mean GI50s 0.877-2.92 ng/mL).
- Displays cytotoxic activities against PC-6 and PC-6/SN2-5 cells.
- Stabilizes DNA-TopoI complexes in PC-6 and PC-6/SN2-5 cells.
- Exhibits antitumor activities in mouse models without toxic death.
- Highly inhibits MIA-PaCa and BxPC-3 primary tumor growth in early-stage models.
- Suppresses BxPC-3 lymphatic metastasis and eliminates lung metastasis in late-stage cancer models.
Chemscene Fmoc-Tle-OH | 25g | CS-W009804 | 98% | 132684-60-7 | MFCD00065649 | 353 42 | C21H23NO4
Chemscene | Fmoc-Tle-OH | 25g | CS-W009804 | 98% | 132684-60-7 | MFCD00065649 | 353 42 | C21H23NO4
Chemscene N-Isopropylbenzylamine | 500g | CS-W020642 | 98% | 102-97-6 | MFCD00008863 | 149 24 | C10H15N
Chemscene | N-Isopropylbenzylamine | 500g | CS-W020642 | 98% | 102-97-6 | MFCD00008863 | 149 24 | C10H15N
Medchemexpress LLC Anti-Mouse VEGFR-2 A 1mg | 1mg
Anti-Mouse VEGFR-2 Antibody (DC101) is a rat anti-mouse VEGFR2 monoclonal antibody Anti-Mouse VEGFR-2 Antibody (DC101) inhibits tumor angiogenesis by blocking the binding of VEGF and VEGFR2 Anti-Mouse VEGFR-2 Antibody (DC101) promotes immune cell infiltration and induces tumor cell apoptosis Anti-Mouse VEGFR-2 Antibody (DC101) can be used for researches on various types of cancer such as melanoma lung cancer and breast cancer [1][2][3][4][5][6]
Medchemexpress LLC Etomoxir sodium salt | 828934-41-4 | MFCD07787411 | >98.0% | 320.74 g/mol | C15H18ClNaO4 | 10 MG
Etomoxir sodium salt is the sodium salt form of etomoxir, an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT1a) used in research to inhibit fatty acid oxidation and study metabolic pathways. Supplied as a solid suitable for laboratory experiments.
- Irreversible CPT1a inhibitor for fatty acid oxidation studies
- High purity suitable for research applications
- Sodium salt form improves handling and solubility in polar solvents
- Used in metabolic, apoptosis, and mitochondrial research
- Typically stored at low temperature to maintain stability
Medchemexpress LLC a-Fluoromethylhistid 1mg | 81839-27-2 | 260.09 g/mol | C7H12Cl2FN3O2 | 1 MG
α-Fluoromethyl-L-histidine dihydrochloride is the dihydrochloride salt of α-fluoromethylhistidine, used as an irreversible inhibitor of histidine decarboxylase in biochemical research to reduce histamine levels. Supplied for research use only.
- Irreversible inhibitor of histidine decarboxylase.
- Reduces histamine levels in experimental models.
- Supplied as the dihydrochloride salt to improve solubility and stability.
- Molecular weight approximately 260.09 g/mol.
- Purity reported at >98% by some suppliers.
Apexbio Technology LLC Ibutamoren Mesylate 159752-10-0 10mg
Ibutamoren mesylate (CAS 159752-10-0) also known as MK-0677 is an orally bioavailable nonpeptide growth hormone (GH) secretagogue It acts by stimulating GH release via activation of ghrelin receptors located in the pituitary and hypothalamus distinct from the classical GH-releasing hormone receptor Administration of ibutamoren mesylate results in elevated plasma concentrations of growth hormone and insulin-like growth factor 1 (IGF-1) without significantly affecting cortisol levels This compound is under investigation for its ability to enhance muscle mass and bone mineral density and is being studied as a potential therapy for conditions involving GH deficiency or age-related frailty